Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences

Prof. Dr. Andreas Janshoff


  • 1987–1989 Studies of Biology at the University of Münster
  • 1989–1994 Studies of Chemistry at the University of Münster, with honor
  • 1994–1997 PhD thesis under supervision of Prof. Dr. H.-J. Galla
  • 1997–1998 Postdoctoral Researcher at the Scripps Research Institute (La Jolla, CA, USA)
  • 1999–2001 Habilitation in Biochemistry at the University of Münster in the group of Prof. Dr. H.-J. Galla and Prof. Dr. H. Fuchs
  • 2001–2006 Associate Professor (C3) for Physical Chemistry at the University of Mainz
  • 2006–2008 Full Professor (W3) for Biophysical Chemistry at the University of Mainz
  • since 2008 Full Professor (W3) for Biophysical Chemistry at the University of Göttingen
  • 2013 – 2015 Dean of the Faculty of Chemistry in Göttingen



Major Research Interests


  • Membrane Biophysics
  • Cell mechanics
  • Sensor design
  • Single-molecule force spectroscopy




Homepage Department/Research Group
http://www.uni-goettingen.de/de/208570.html


Selected Recent Publications


  • Nietmann, P., Kaub, K., Suchenko, A., Stenz, S., Warnecke, C., Balasubramanian, M.K., Janshoff A Cytosolic actin isoforms form networks with different rheological properties that indicate specific biological function. Nat. Commun. 14, 7989 (2023). Doi: 10.1038/s41467-023-43653-w.

  • Skamrahl, M., Schünemann, J., Mukenhirn, M., Pang, H., Gottwald, J., Jipp, M., Ferle, M., Rübeling, A., Oswald, T. A., Honigmann, A., Janshoff A Cellular Segregation in Cocultures Is Driven by Differential Adhesion and Contractility on Distinct Timescales. Proc. Natl. Acad. Sci. USA 120, e2213186120 (2023). Doi: 10.1073/pnas.2213186120.

  • Skamrahl, M., Pang, H., Ferle, M., Gottwald, J., Ruebeling, A., Maraspini, R., Honigmann, A., Oswald, T.A., Janshoff A Tight junction ZO proteins maintain tissue fluidity, ensuring efficient collective cell migration. Adv. Sci. 8, 2170122 (2021). DOI: 10.1002/advs.202100478.

  • Cordes, A., Witt, H., Gallemí-Pérez, A., Brückner, B., Grimm, F., Vache, M., Oswald, T., Bodenschatz, J., Flormann, D., Lautenschläger, F., Tarantola, M.*, Janshoff A Prestress and Area Compressibility of Actin Cortices Determine the Viscoelastic Response of Living Cells. Phys. Rev. Lett. 125, 068101 (2020). DOI: 10.1103/PhysRevLett.125.068101.

  • Hubrich, H., Mey, I.P., Brückner, B.R., Mühlenbrock, P., Nehls, S., Grabenhorst, L., Oswald, T., Steinem, C., Janshoff A, Viscoelasticity of Native and Artificial Actin Cortices Assessed by Nanoindentation Experiments. Nano Lett. 20, 6329–6335 (2020). DOI: 10.1021/ acs.nanolett.0c01769.

  • Block J, Witt H, Candelli A, Danes JC, Peterman EJ, Wuite GJ, Janshoff A, Köster S (2018) Viscoelastic properties of vimentin originate from nonequilibrium conformational changes. Science Advances, 4(6), eaat1161.

  • Seiwert D, Witt H, Janshoff A, Paulsen H (2017) The non-bilayer lipid MGDG stabilizes the major light-harvesting complex (LHCII) against unfolding. Scientific Reports, 7, 5158.

  • Schütte OM, Mey I, Enderlein J, Savić F, Geil B, Janshoff A, Steinem C (2017) Size and mobility of lipid domains tuned by geometrical constraints. Proceedings of the National Academy of Sciences, 114 (30), E6064-E6071.

  • Baronsky T, Ruhlandt D, Brückner BR, Schäfer J, Karedla N, Isbaner S, Hähnel D, Gregor I, Enderlein J, Janshoff A, Chizhik AI (2017) Cell-Substrate Dynamics of the Epithelial-to-Mesenchymal Transition. Nano Letters, 17 (5), 3320-3326.

  • Brückner BR, Nöding H, Janshoff A (2017) Viscoelastic Properties of Confluent MDCK II Cells Obtained from Force Cycle Experiments. Biophysical Journal 112 (4), 724-735.