Original articles

Rauwald HW, Maucher R, Dannhardt G, Kuchta K. Dihydroisocoumarins, Naphthalenes, and Further Polyketides from Aloe vera and A. plicatilis: Isolation, Identification and Their 5-LOX/COX-1 Inhibiting Potency. Molecules. 2021; 26(14): 4223.

Kuchta K, Hladikova M, Thomsen M, Nahrstedt A, Schmidt M. Kava ( Piper methysticum) Extract for the Treatment of Nervous Anxiety, Tension and Restlessness. Drug Res (Stuttg). 2021; 71(2): 83-93.

Yang C, Chen G, Kuchta K, Zhang W. Effect of Three-Dimensional (3d) Simulated Microgravity Culture on Morphology and Secretory Function of Murine Pituitary Cells. Postępy Biologii Komórki 2020; 47(2), 209-220.

Houriet J, Allard PM, Queiroz EF, Marcourt L, Gaudry A, Vallin L, Li S, Lin Y, Wang R, Kuchta K Wolfender JL. A Mass Spectrometry Based Metabolite Profiling Workflow for Selecting Abundant Specific Markers and Their Structurally Related Multi-Component Signatures in Traditional Chinese Medicine Multi-Herb Formulae. Front Pharmacol. 2020; 11: 578346. doi:10.3389/fphar.2020.578346

Kuchta K*, Schmidt M. Safety of medicinal comfrey cream preparations ( Symphytum officinale s.l.): The pyrrolizidine alkaloid lycopsamine is poorly absorbed through human skin. Regul Toxicol Pharmacol. 2020; 118: 104784. (*co-correspondence author)

Yao J, Qiao H, Jin Z, Wang R, Huang H, Fang L, Chen Y, Tai K, Chen Y, Doeppner TR*, Chen Z*, Kuchta K*: Ginkgo biloba and Its Constituent 6-hydroxykynurenic-acid as well as Its Proanthocyanidins Exert Neurorestorative Effects against Cerebral Ischemia. Planta Med 86(10): 696-707, 2020. (*co-correspondence author)

Kuchta K*, Tung NH, Ohta T, Uto T, Raekiansyah M, Grötzinger K, Rausch H, Shoyama Y, Rauwald HW, Morita K: The old pharmaceutical oleoresin labdanum of Cistus creticus L. exerts pronounced in vitro anti-dengue virus activity. J Ethnopharmacol 257: 112316, 2020. (*correspondence author)

Rauwald HW, Liebold T, Grötzinger K, Lehmann J, Kuchta K: Labdanum and Labdanes of Cistus creticus and C. ladanifer: Anti-Borrelia activity and its phytochemical profiling. Phytomedicine 60: 152977, 2019.

Yao J, He H, Xue J, Wang J, Jin H, Wu J, Hu J, Wang R, Kuchta K*: Mori ramulus (Chin.Ph.) - the dried twigs of Morus alba L. / Part 1: Discovery of two novel coumarin glycosides from the anti-hyperuricemic ethanol extract. Molecules 24: 629ff, 2019. (*correspondence author)

Kuchta K, de Nicola P, Schmidt M: Randomized, dose-controlled double-blind trial: Efficacy of an ethanolic kava ( Piper methysticum rhizome) extract for the treatment of anxiety in elderly patients. Traditional & Kampo Medicine 5(1): 3-10, 2018.

Yao JB, Du X, Jin HH, Fang L, Min H, Qiao HX, Wang RW, Kuchta K*: Seasonal Variability of Genistein and 6-Hydroxykynurenic Acid Contents in Ginkgo biloba Leaves from Different Areas of China. Natural Product Communications 12(8): 1241-1244, 2017. (*correspondence author)

He YJ, Kuchta K*, Deng YM, Cameron S, Lin Y, Liu XY, Ye GR, Lv X, Kobayashi Y, Shu JC: Curcumin Promotes Apoptosis of Activated Hepatic Stellate Cells by Inhibiting Protein Expression of the MyD88 Pathway. Planta Med 83(18): 1392-1396, 2017. (*co-correspondence author)

Kuchta K, Xiang Y, Huang S, Tang Y, Peng X, Wang X, Zhu Y, Li J, Xu J, Lin Z, Pan T: Celastrol, an active constituent of the TCM plant Tripterygium wilfordii Hook.f., inhibits prostate cancer bone metastasis. Prostate Cancer & Prostatic Diseases 20, 156-164, 2017.

Kuchta K*, Ortwein J, Çaliş İ, Volk RB, Rauwald HW: Identification of Cardioactive Leonurus and Leonotis Drugs by Quantitative HPLC Determination and HPTLC Detection of Phenolic Marker Constituents. Natural Product Communications 11: 1129-1133, 2016. (*co-correspondence author)

He YJ, Kuchta K*, Lv X, Lin Y, Ye GR, Liu XY, Song HD, Wang LX, Kobayashi Y, Shu JC: Curcumin, the main active constituent of turmeric (Curcuma longa L.), induces apoptosis in hepatic stellate cells by modulating the abundance of apoptosis-related growth factors. Z Naturforsch C 70: 281-285, 2015. (*co-correspondence author)

Rauwald HW, Savtschenko A, Merten A, Rusch C, Appel K, Kuchta K*: GABAA Receptor Binding Assays of Standardized Leonurus cardiaca and Leonurus japonicus Extracts as Well as Their Isolated Constituents. Planta Med 81: 1103-1110, 2015. (*co-correspondence author)

Watanabe E, Kuchta K, Kimura M, Rauwald HW, Kamei T, Imanishi J: Effects of bergamot (Citrus bergamia (Risso) Wright & Arn.) essential oil aromatherapy on mood states, parasympathetic nervous system activity, and salivary cortisol levels in 41 healthy females. Forsch Komplementmed 22: 43-49, 2015.

Wang R, Kobayashi Y, Lin Y, Rauwald HW, Fang L, Qiao H, Kuchta K*: A phytosterol enriched refined extract of Brassica campestris L. pollen significantly improves benign prostatic hyperplasia (BPH) in a rat model as compared to the classical TCM pollen preparation Qianlie Kang Pule'an Tablets. Phytomedicine 22: 145-152, 2015. (*correspondence author)

Wang R, Kobayashi Y, Lin Y, Rauwald HW, Yao J, Fang L, Qiao H, Kuchta K*: HPLC quantification of all five ginkgolic acid derivatives in Ginkgo biloba extracts using 13 : 0 ginkgolic acid as a single marker compound. Planta Med 81: 71-78, 2015. (*correspondence author )

Li S, Tamaru N, Lin Y, Wang R, Kuchta K, Sato N, Iwasaki S, Kobayashi Y: Interesting clinical report on the effects of atopic dermatitis therapy in 102 patients with topical TCM preparations. Clinical Journal of Traditional Chinese Medicine 35: 46-50, 2014. (李頌華、田丸直美、林宇、王如偉、ケニー・クフタ、佐藤直人、岩崎純夫、小林裕太：興味深い臨床報告　アトピー性皮膚炎102例における複方苦参製剤の外用効果。中医臨床)

Kuchta K, Ortwein J, Hennig L, Rauwald HW: 1H-qNMR for direct quantification of stachydrine in Leonurus japonicus and L. cardiaca. Fitoterapia 96: 8-17, 2014.

Watanabe E, Kimura M, Kuchta K, Kamei T, Imanishi J: Effects of Essential Oil Odor Exposure on Psychophysiological and Immunological Parameters of Fatigue due to Computer-Related Tasks. Journal of the Japanese Society for Complementary and Alternative Medicine 10: 107-115, 2013. (渡邉映理、木村真理、ケニー・クフタ、亀井勉、今西二郎：芳香浴によるパーソナルコンピュータ作業の疲労軽減効果−生理、心理、免疫学的指標による検討。日本補完代替医療学会誌)

Watanabe E, Kuchta K, Kamei T, Mazda O: The effects of performing tasks on Visual Display Terminals for 90 minutes on salivary cortisol, moods and work efficiency in healthy men. Journal of the Japan Society of Physiological Anthropology 18: 105-113, 2013. (渡邉映理、ケニー･クフタ、亀井勉、松田修：90分間のVDT (Visual Display Terminals) 作業が健常男性の唾液中コルチゾールおよび気分、作業効率に及ぼす影響。日本生理人類学会誌)

Kuchta K, Volk RB, Rauwald HW: Stachydrine in Leonurus cardiaca, Leonurus japonicus, Leonotis leonurus: Detection and quantification by instrumental HPTLC and 1H-qNMR analyses. Pharmazie 68: 534-540, 2013.

Li S, Kuchta K*, Tamaru N, Lin Y, Iwasaki S, Wang R, Kobayashi Y, Rauwald HW, Kamei T: Efficacy of a Novel Herbal Multi Component TCM Therapy Approach in Patients with Atopic Dermatitis. Forsch Komplementmed 20: 189-196, 2013. (*co-correspondence author)

Watanabe E, Kimura M, Kishida S, Kuchta K, Kamei T, Imanishi J: Practical Aromatherapy Massage: Reciprocal Psychological Effects on Patients and Therapists. Journal of the Japanese Society of Integrative Medicine 6: 93-103, 2013. (渡邉映理、木村真理、岸田聡子、ケニー・クフタ、亀井勉、今西二郎：アロマセラピー・マッサージ実践による施術される側、および施術する側への心理相互効果。日本統合医療学会誌)

Watanabe E, Kimura M, Kuchta K, Kamei T, Imanishi J: Effects of bergamot essential oil on the autonomic nervous system and general emotional state. Aroma Research 54: 150-154, 2013. (渡邉映理、木村真理、ケニー・クフタ、亀井勉、今西二郎：ベルガモット精油による芳香浴の自律神経系および情動に及ぼす効果)

Kuchta K, Ortwein J, Rauwald HW: Leonurus japonicus, Leonurus cardiaca, Leonotis leonurus: A novel HPLC study on the occurrence and content of the pharmacologically active guanidino derivative leonurine. Pharmazie 67: 973-979, 2012.

Flemmig J, Kuchta K, Arnhold J, Rauwald HW: Olea europaea leaf (Ph.Eur.) extract as well as several of its isolated phenolics inhibit the gout-related enzyme xanthine oxidase. Phytomedicine 18: 561-566, 2011.

Ritter M, Melichar K, Strahler S, Kuchta K, Schulte J, Sartiani L, Cerbai E, Mugelli A, Mohr FW, Rauwald HW, Dhein S: Cardiac and Electrophysiological Effects of Primary and Refined Extracts from Leonurus cardiaca L. (Ph.Eur.). Planta Medica 76: 572-582, 2010.

Trautwein K, Kühner S, Wöhlbrand L, Halder T, Kuchta K, Steinbüchel A, Rabus R: Solvent Stress Response of the Denitrifying Bacterium “Aromatoleum aromaticum” Strain EbN1. Applied and Environmental Microbiology 74: 2267-2274, 2008.

Kuchta K, Chi L, Fuchs H, Pötter M, Steinbüchel A: Studies on the Influence of Phasins on Accumulation and Degradation of PHB and Nanostructure of PHB Granules in Ralstonia eutropha H16. Biomacromolecules 8: 657-662, 2007.

Scheidgen-Kleyboldt G, Kuchta K, Kiy T, Tiedtke A: Production of Secreted Enzymes by Continuous High-cell-density Cultivation of Colpidium campylum. European Journal of Protistology 39: 455-460, 2003.