Kimberly Quililan

EDUCATION

College / University

University of the Philippines Diliman

Highest Degree

Bachelor of Science

Major Subjects

Molecular Biology and Biotechnology

Quililan

Country

Philippines

Lab Experience

gDNA extraction from tumor samples, gene cloning, site-directed mutagenesis, western blot, RNA extraction and qPCR, Hi-C, Capture Hi-C; transfection via lipofection and electroporation, immunocytochemistry, LDH-based cytotoxicity assays, luciferase assays, and cancer assays (wound migration and Caspase 3/7 GLO apoptosis assay), Fluorescence microscopy; R

Projects / Research

  • 2020: “3D chromatin interactions of the immunoglobulin locus in the context of lymphoma-associated translocations.” Beekman Group, Centre for Genomic Regulation (CRG), Barcelona, Spain.
  • 2019 – 2020: Drug Discovery: “Screening synthetic compounds and lead hits for their ADME-Tox properties”. National Institute of Molecular Biology and Biotechnology, Philippines.
  • 2019: “Investigating promoter preferences of cofactor and viral synthetic activators using STAP-Seq in human cells.” Stark Group, IMP, Vienna Biocenter, Vienna, Austria.
  • 2018: “Profiling and functional characterization of novel mutations in the EGFR pathways among Filipino patients.” National Institute of Molecular Biology and Biotechnology, Philippines.
  • 2017 – 2018: Undergraduate Thesis: “Reciprocal regulation of the putative ceRNAs PIK3CA and ZNF148 through miR-506.” University of the Philippines Diliman, Philippines.

Scholarships / Awards

2020 – 2021: Stipend by the International Max Planck Research School.
2014 – 2018: Gerry Roxas Leadership Scholarship.

SCIENTIFIC INTERESTS AND GOALS

I am mainly interested in the mechanisms that govern eukaryotic transcription. I am curious to know how cofactors and transcription factors work with Pol II to activate transcription. In line with this, I am also keen to investigate the role of enhancers where these factors bind to. Lastly, I would like to understand how an enhancer associates with its specific promoter in 3D and how alterations in genome topology would impact gene expression.