Delong Li

EDUCATION

College / University

Goethe University Frankfurt/Main

Highest Degree

Bachelor of Science

Major Subjects

Biochemistry

Li

Country

Germany

Lab Experience

Classical biochemical methods (protein/organelle purification, pulldowns, SDS-PAGE, Western blot, ATP assays), yeast genetics (PCR, cloning, transformation, genetic characterization), fluorescence light microscopy (widefield and CLSM).

Projects / Research

  • 2021: Identification of the selective autophagy receptor for clearance of yeast stress granules, Bachelor thesis, Max Planck Institute of Biophysics Frankfurt, Dr. Wilfling
  • 2020: Enrichment of Microsomes containing Peptide Loading Complex (PLC) with Magnetic Beads and Quantum dots & FACS, Research internship, Goethe University Frankfurt, Institute of Biochemistry, Prof. Tampé

Scholarships / Awards

2021 – 2022: Stipend by the International Max Planck Research School
Since 2020: Scholarship by the German Academic Scholarship Foundation (Studienstiftung des deutschen Volkes)

SCIENTIFIC INTERESTS AND GOALS

I am fascinated by how macromolecular machines work and are being kept in place by the cell. Without any knowledge about their own biochemistry, all the proteins function flawlessly, like in an arranged orchestra. My goal is to try to characterize their purpose and discover the mechanisms that lie behind their function. And lastly, to obtain a deep understanding of how these proteins operate in a cellular context with, e.g., 3D cryo-EM/ET or super resolution microscopy (STED, STORM).
One step further, I'd like to explore the countless ways how cells can convey information about their current status to other cells. This cellular signaling is essential for a physiological response when facing critical circumstances in a tissue or organ. Understanding the signaling mechanisms through genomics/proteomics approaches can help to treat dreadful diseases and one day lead to cures.