Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences

Lutz, Susanne, Prof. Dr.

Professor (W2) for Biochemical Pharmacology


  • since 2011: W2 Professor for Biochemical Pharmacology, University Medical Center, Göttingen
  • since 2010: Head of the «GPCR-signaling Research unit», Pharmacology, University Medical Center, Göttingen
  • 2002-2010:Postdoctoral Fellow, Institute of Clinical and Experimental Pharmacology and Toxicology, Medical Faculty Mannheim, University of Heidelberg, Habilitation 2010
  • 1997-2002: Graduate research assistant, Cardiology department, Faculty of Medicine, University of Heidelberg. Degree: Dr. rer. nat.
  • 1996-1997: Graduate research assistant, Institute of Human Genetics, Faculty of Medicine, University of Heidelberg
  • 1990-1995: Studies of Biology, University of Konstanz. Degree: Dipl. Biol.



Major Research Interests

Cardiac signal transduction, GPCR and monomeric G protein signaling, cytoskeleton regulation, mechanisms in cardiac fibrosis, biomechanical tissue analysis, cell biology, and cardiovascular science.


Homepage Department/Research Group

https://pharmacology.umg.eu/research/lutz-lab/


Selected Recent Publications


  • Santos GL, DeGrave AN, Rehman A, Al Disi S, Xhaxho K, Schröder H, Bao G, Meyer T, Tiburcy M, Dworatzek E, Zimmermann WH, Lutz S (2022). Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues. Biomater Adv. 139:213041.
  • Levay MK, Krobert KA, Vogt A, Ahmad A, Jungmann A, Neuber C, Pasch S, Hansen A, Müller OJ, Lutz S*, Wieland T* (2022). GS3L allows for an M2 muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes. Basic Res Cardiol. 117(1):8. *shared senior authorship
  • Weber P, Baltus D, Jatho A, Drews O, Zelarayan LC, Wieland T, Lutz S (2021) RhoGEF17-An Essential Regulator of Endothelial Cell Death and Growth. Cells. 10(4):741.
  • Kittana N, Assali M, Zimmermann WH, Liaw N, Santos GL, Rehman A, Lutz S (2021) Modulating the Biomechanical Properties of Engineered Connective Tissues by Chitosan-Coated Multiwall Carbon Nanotubes. Int J Nanomedicine. 16:989-1000.
  • Santos GL, Hartmann S, Zimmermann WH, Ridley A, Lutz S (2019) Inhibition of Rho-associated kinases suppresses cardiac myofibroblast function in engineered connective and heart muscle tissues. J Mol Cell Cardiol. 134:13-28.
  • Dworatzek E, Mahmoodzadeh S, Schriever C, Kusumoto K, Kramer L, Santos G, Fliegner D, Leung YK, Ho SM, Zimmermann WH, Lutz S, Regitz-Zagrosek V (2019) Sex-specific regulation of collagen I and III expression by 17β-Estradiol in cardiac fibroblasts: role of estrogen receptors. Cardiovasc Res. 115(2):315-327