Valentina Manzini

EDUCATION

College / University

University of Sussex, England

Highest Degree

Bachelor of Science (Honors)

Major Subjects

Genetics and Genomics, Cell Biology, Gene Expression, Microbiology, Clinical Biochemistry, Cell Signalling

Country

Italy

Lab Experience

Molecular biology techniques including plasmid preparation, random and site-directed mutagenesis, subcloning, restriction digests, DNA sequencing, PCR, western/southern blotting, trichloroacetic acid protein precipitation, chromatin immunoprecipitation. Yeast techniques with both S.cerevisiae and S. pombe including transformation, yeast genomic DNA preparation, plasmid rescue, yeast two-hybrid,spot test assay and gap-repair.

Projects / Research

06/2014 – 09/2014: “Mechanism and evolutionary conservation of the interaction between SUMO and telomeric protein Stn1”. JRA summer project, University of Sussex
09/2014 – 01/2015: “Regulation of telomerase at fission yeast telomeres”. Bachelor’s thesis, University of Sussex

Scholarships / Awards

2015 – 2016:	Stipend by the International Max Planck Research School
2014:	Junior Research Associate (JRA) Bursary by the University of Sussex

SCIENTIFIC INTERESTS AND GOALS

I am currently interested in various areas of genomic regulation, especially in the mechanisms of gene expression and epigenetic regulation in both health and disease states. I would like to better understand how each step of gene expression is modulated at the level of nuclear genome and mRNA using biophysics and molecular biology approaches. I am looking forward to exploring research topics such as genome stability, chromatin domains and RNA maturation in order to broaden my knowledge and understand my career path.