Molecular Biology (MSc/PhD)

Meline Macher

EDUCATION

College / University

University of Göttingen

Highest Degree

Bachelor of Science

Major Subjects

Biology
maurer

Country

Germany

Lab Experience

Mouse models, cell culture (generation and culture of primary human keratinocytes with mitotic inactivated embryonic mouse fibroblasts), histological staining (HE, IF, IHC, FISH, standard staining methods), flow cytometry and cell sorting, DNA/RNA isolation, cDNA synthesis, agarose gel electrophoresis, SDS-PAGE, PCR/qPCR, Sanger sequencing, SELEX, transformation/cloning, isolation and IF staining of individual hair follicles.

Projects / Research

  • 03/2017 – 07/2017 “Histological and cellular characterization of CD4-positive cells of murine and human skin”, Bachelor`s thesis, Human Genetics, University Medical Center Göttingen
  • 08/2013 – 12/2013 “Generating ssDNA-aptamers to bind the active site of fucosyltransferase 9 using the SELEX method”, Internship at the Institute for Biochemistry and Molecular Biology, University of Hamburg

Scholarships / Awards

2017 – 2018: Stipend by the International Max Planck Research School

SCIENTIFIC INTERESTS AND GOALS

Over the past years my scientific interest has been focused on the formation and occurrence of human diseases at the molecular level. Therefore, I am fascinated how tiny errors in our genome arise, for example, during mitosis or meiosis and how they can have such vast effects on the human body. I am also interested in the resulting proteins and their possibly misled interaction within cell signaling pathways. I think it is very important to understand the cause of a disease at the molecular level and integrate this knowledge into the intricate network of the whole organism to interpret and cure a disease successfully. For this reason, it is important to combine the knowledge of many different fields of biology, such as genetics, biochemistry, developmental biology and cell biology. During the Molecular Biology Program I wish to expand my knowledge in these fields to specify my research focus. Furthermore, I am excited to explore new fields of molecular life sciences I am not familiar with yet.