Free Floater Nachwuchsgruppe - Angewandte Synthetische Biologie

Angewandte Synthetische Biologie

Synthetic Biology is an actively growing field of the life sciences that combines elements from biology and engineering with the aim to design and create life forms with new, unprecedented properties and functions. Synthetic biologists have increased the coding potential of several organisms to allow genetic incorporation of additional “unnatural” amino acids into proteins. These unnatural amino acids have unique chemical or biophysical properties or carry naturally occurring (post-translational) modifications and are therefore fascinating new tools to investigate cellular processes.
Using these tools we develop new strategies to introduce spectroscopic probes into proteins to study the dynamic properties of chromatin. We are also interested in the effect of the post-translational acetylation of lysine residues on protein structure and function.