Publications by IRTG 2172 PRoTECT members


  • Lüdke, D., Roth, C., Kamrad, S.A., Messerschmidt, J., Hartken, D., Appel, J., Hörnich, B.F., Yan, Q., Kusch, S., Klenke, M., Gunkel, A., Wirthmueller, L. and Wiermer, M.: Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1. Plant J (2021)

  • Ao, K., Tong, M., Li, L., Lüdke, D., Lipka, V., Chen, S., Wiermer, M. and Li, X.: SCFSNIPER7 controls protein turnover of unfoldase CDC48A to promote plant immunity. NewPhytol (2021)

  • Mohnike, L., Rekhter, D., Huang, W., Feussner, K., Hainan Tian, H., Herrfurth, C.,
    Zhang, Y., and Feussner, I.: The glycosyltransferase UGT76B1 modulates N-hydroxy-pipecolic acid homeostasis and plant immunity. The Plant Cell (2021)


  • Dreischhoff, S., Das, I. S., Jakobi, M., Kasper, K., and Polle, A.: Local Responses and Systemic Induced Resistance Mediated by Ectomycorrhizal Fungi. Frontiers in Plant Science (2020)

  • Budimir, J., K. Treffon, A. Nair, C. Thurow and C. Gatz: Redox-active cysteines in TGACG-BINDING FACTOR 1 (TGA1) do not play a role in salicylic acid- or pathogen-induced expression of TGA1-regulated target genes in Arabidopsis thaliana. New Phytol., doi:10.1111/nph.16614 (2020).

  • Horianopoulos, L., G. Hu, M. Caza, K. Schmitt, P. Overby, J. Johnson, O. Valerius, G.H. Braus and J.W. Kronstad: The Novel J-Domain Protein Mrj1 Is Required for Mitochondrial Respiration and Virulence in Cryptococcus neoformans. mBio 11 (3) e01127-20; doi:10.1128/mBio.01127-20 (2020).

  • Huang W., Y. Wang, X. Li and Y. Zhang: Biosynthesis and regulation of salicylic acid and N-hydroxypipecolic acid in plant immunity. Mol Plant. 13(1):31-41, doi:10.1016/j.molp.2019.12.008 (2020).

  • Leonard, M., A. Kühn, R. Harting, I. Maurus, A. Nagel, J. Starke, H. Kusch, O. Valerius, K. Feussner, I. Feussner, A. Kaever, B. Morgenstern, D. Becher, M. Hecker, S.A. Braus-Strohmeyer, J.W. Kronstad and G.H.Braus: V. longisporum elicits media-dependent secretome responses with a capacity to distinguish between plant-related environments. Frontiers in Microbiology 11, doi:10.3389/fmicb.2020.01876 (2020).

  • Lewandowska, M., Keyl, A. and Feussner, I.: Wax biosynthesis in response to danger: its regulation upon abiotic and biotic stress. New Phytol. 227(3):698-713, doi:10.1111/nph.16571 (2020).

  • Lüdke, D., C. Roth, S.A. Kamrad, J. Messerschmidt, D. Hartken, J. Appel, B.F. Hörnich, Q. Yan, S. Kusch, M. Klenke, A. Gunkel, L. Wirthmueller and M. Wiermer: Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1. bioRxiv 2020.05.09.084020, doi:10.1101/2020.05.09.084020 (2020).

  • Schmitz, L., J.W. Kronstad and K. Heimel: Conditional gene expression reveals stage‐specific functions of the unfolded protein response in the Ustilago maydis–maize pathosystem. Molecular Plant Pathology 21: 258-271, doi:10.1111/mpp.12893 (2020).

  • Starke, J., R. Harting, I. Maurus, R. Bremenkamp, J.W. Kronstad and G.H. Braus: Unfolded protein response and scaffold independent pheromone MAP kinase signalling control Verticillium dahliae growth, development and plant pathogenesis. bioRxiv 941450, doi:10.1101/2020.02.10.941450 (2020).

  • Sun, T., J. Huang , Y. Xu , V. Verma , B. Jing , Y. Sun , A. Ruiz Orduna , H. Tian , X. Huang , S. Xia , L. Schafer, R. Jetter, Y. Zhang and X. Li: Redundant CAMTA transcription factors negatively regulate the biosynthesis of salicylic acid and N-hydroxypipecolic acid by modulating the expression of SARD1 and CBP60g. Mol Plant.13(1):144-156, doi:10.1016/j.molp.2019.10.016 (2020).

  • Vishwanathan, K., K. Zienkiewicz, Y. Liu, D. Janz, I. Feussner, A. Polle and C.H. Haney: Ectomycorrhizal fungi induce systemic resistance against insects on a non‐mycorrhizal plant in a CERK1‐dependent manner. New Phytol.,doi:10.1111/nph.16715 (2020).


  • Guzha, A., R. McGee, D. Hartken, P. Scholz, D. Luedke, K. Bauer, M. Wenig, K. Zienkiewicz, I. Feussner, A.C. Vlot, M. Wiermer, G. Haughn, and T. Ischebeck: The cell-wall-localised BETA-XYLOSIDASE 4 contributes to immunity of Arabidopsis against Botrytis cinerea. bioRxiv 851170, doi:10.1101/851170 (2019).

  • Haroth, S., K. Feussner , A.A. Kelly, K. Zienkiewicz, A. Shaikhqasem, C. Herrfurth and I. Feussner: The glycosyltransferase UGT76E1 significantly contributes to 12-O-glucopyranosyl-jasmonic acid formation in wounded Arabidopsis thaliana leaves. J Biol Chem. 294(25):9858-9872, doi: 10.1074/jbc.RA119.007600 (2019).

  • Horianopoulos, L. C. and J.W. Kronstad: Connecting iron regulation and mitochondrial function in Cryptococcus neoformans. Current Opinions in Microbiology 52, 7-13, doi:10.1016/j.mib.2019.04.002 (2019),

  • Kareem, Z.J.#, L. Su#, A. Rathgeb, A. Sirrenberg, F. Hadacek, A.H.A.H. Rashid and P. Karlovsky: Small scale bioreactor for sterile hydroponics and hairy roots: metabolic diversity and salicylic acid exudation by hairy roots of Hyoscyamus niger. Applied Sciences 9:3044, doi:10.3390/app9153044 (2019). # These authors contributed equally to this work

  • Kretschmer M, D. Damoo, A. Djamei and J. Kronstad: Chloroplasts and Plant Immunity: Where Are the Fungal Effectors? Pathogens 9(1) pii: E19, doi: 10.3390/pathogens9010019 (2019).

  • Li, N., M. Muthreich, L.J. Huang, C. Thurow, T. Sun, Y. Zhang and C. Gatz: TGACG-BINDING FACTORs (TGAs) and TGA-interacting CC-type glutaredoxins modulate hyponastic growth in Arabidopsis thaliana. New Phytol. 221(4):1906-1918, doi: 10.1111/nph.15496 (2019).

  • Liang, W., S. van Wersch, M. Tong and X. Li: TIR‐NB‐LRR immune receptor SOC 3 pairs with truncated TIR‐NB protein CHS 1 or TN 2 to monitor the homeostasis of E3 ligase SAUL. New Phytologist, 221(4), 2054-2066 doi: 10.1111/nph15534(2019).

  • Pinter, N., C.A. Hach, M. Hampel, D. Rekhter, K. Zienkiewicz, I. Feussner, A. Poehlein, R. Daniel, F. Finkernagel and K. Heimel: Signal peptide peptidase activity connects the unfolded protein response to plant defense suppression by Ustilago maydis. PLoS Pathogens 15, e1007734. doi: 10.1371/journal.ppat.1007734 (2019).

  • Rekhter, D., D. Lüdke, Y. Ding, K. Feussner, K. Zienkiewicz, V. Lipka, M. Wiermer, Y. Zhang and I. Feussner: Isochorismate-derived biosynthesis of the plant stress hormone salicylic acid. Science 365(6452):498-502 (2019). Link

  • Rekhter, D., L. Mohnike, K. Feussner, K. Zienkiewicz, Y. Zhang and I. Feussner: Enhanced Disease Susceptibility 5 (EDS5) is required for N-hydroxy pipecolic acid formation. bioRxiv 630723, doi:101101/630723 (2019).

  • Resemann, H.C., M. Lewandowska, J. Gömann and I. Feussner: Membrane lipids, waxes and oxylipins in the moss model organism Physcomitrella patens. Plant Cell Physiol. 60, 1166-1175 doi:10.1093/pcp/pcz006 (2019).

  • Schmitz L., M.A. Schwier and K. Heimel: The Unfolded Protein Response Regulates Pathogenic Development of Ustilago maydis by Rok1-Dependent Inhibition of Mating-Type Signaling. mBio 10 (6) e02756-19, doi: 10.1128/mBio.02756-19 (2019).

  • Šola, K., E.J. Gilchrist, D. Ropartz, L. Wang, I. Feussner, S.D. Mansfield, M.C. Ralet and G.W. Haughn: RUBY, a Putative Galactose Oxidase, Influences Pectin Properties and Promotes Cell-To-Cell Adhesion in the Seed Coat Epidermis of Arabidopsis. Plant Cell 31, 809-831, doi:10.1105/tpc.18.00954 (2019).

  • Thulasi Devendrakumar K., C. Copeland and X. Li: The proteasome regulator PTRE1 contributes to the turnover of SNC1 immune receptor. Mol Plant Pathol. 20(11):1566-1573, doi: 10.1111/mpp.12855 (2019).

  • van Wersch, S. and X. Li: Stronger When Together: Clustering of Plant NLR Disease resistance Genes. Trends in Plant Science 24 (8), 665-784, doi:10.1016/j.tplants.2019.05.005 (2019).

  • Xu, Y., M. Vinas, A. Alsarrag, L. Su, K. Pfohl, M. Rohlfs, W. Schäfer and P. Karlovsky: Bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators. Nat Commun. 10(1):3579 doi:10.1038/s41467-019-11377-5(2019).

  • Yu K., Y. Liu, R. Tichelaar, N. Savant, E. Lagendijk, S.J.L. van Kuijk, I.A. Stringlis, A.J.H. van Dijken, C.M.J. Pieterse, P.A.H.M. Bakker, C.H. Haney and R.L. Berendsen: Rhizosphere-Associated Pseudomonas Suppress Local Root Immune Responses by Gluconic Acid-Mediated Lowering of Environmental pH. Current Biology 29 (22) 3913-3920, doi:10.1016/j.cub2019.09.015 (2019).


  • Bairwa, G., M. Caza, L. Horianopoulos, G. Hu and J. Kronstad: Role of clathrin‐mediated endocytosis in the use of heme and hemoglobin by the fungal pathogen Cryptococcus neoformans. Cellular microbiology 6:e12961 doi: 10.1111/cmi.12961 (2018).

  • Behar, H., S.W. Graham and H. Brumer: Comprehensive cross-genome survey and phylogeny of glycoside hydrolase family 16 members reveals the evolutionary origin of EG16 and XTH proteins in plant lineages. Plant Journal 95(6), 1114-1128, doi:10.1111/tpj.14004 (2018).

  • Bui, T., R. Harting, S.A. Braus‐Stromeyer V. Tran, M. Leonard, A. Höfer, A. Abelmann, F. Bakti, O. Valerius, R. Schlüter, C.E. Stanley, A. Ambrósio and G.H. Braus: Verticillium dahliae transcription factors Som1 and Vta3 control microsclerotia formation and sequential steps of plant root penetration and colonisation to induce disease. New Phytol., 221(4):2138-2159, doi:10.1111/nph.15514 (2018).

  • Cho, M., G. Hu, M. Caza, L.C. Horianopoulos, J.W. Kronstad and W.H. Jung: Vacuolar zinc transporter Zrc1 is required for detoxification of excess intracellular zinc in the human fungal pathogen Cryptococcus neoformans. Journal of Microbiology 56(1), 65-71, doi:10.1007/s12275-018-7475-y (2018).

  • Ding, H., M. Caza, Y. Dong, A.A. Arif, L.C. Horianopoulos, G. Hu, P. Johnson and J.W. Kronstad: ATG genes influence the virulence of Cryptococcus neoformans through contributions beyond core autophagy functions. Infection and immunity 86(9) e00069-18, doi: 10.1128/IAI.00069-18 (2018).

  • Ding, Y. #, T. Sun#, K. Ao, Y.X. Zhang, X. Li and Y. Zhang: Opposite roles of salicylic acid receptors NPR1 and NPR3/NPR4 in transcriptional regulation of plant immunity. Cell 173 (6) 1454-1467, doi:10.1016/j.cell2018.03.044 (2018). #These authors contributed equally to this work

  • Dong, O., K. Ao, F. Xu, K. Johnson, Y. Wu, L. Li, Y. Liu, Y. Huang, E. Rodriguez, X. Chen, S. Chen, Y. Zhang, M. Petersen and X. Li: Individual components of paired typical NLR immune receptors are regulated by distinct E3 ligases. Nature Plant 4, 699-710, doi:10.1038/s41477-018-0216-8 (2018).

  • Horianopoulos, L.C., C.K. Boone, G.G. Samarasekera, G.K. Kandola and B.W. Murray: Selection of the sex‐linked inhibitor of apoptosis in mountain pine beetle (Dendroctonus ponderosae) driven by enhanced expression during early overwintering. Ecology and Evolution. 8(12), 6253-6264, doi:10,1002/ece3.4164 (2018).

  • Kaling, M., A. Schmidt, F. Moritz, M. Rosenkranz, M. Witting, K. Kasper, D. Janz, P. Schmitt-Kopplin, J.P. Schnitzler and A. Polle: Mycorrhiza-triggered transcriptomic and metabolomic networks impinge on herbivore fitness. Plant Physiology 176: 2639-2656, doi:10.1104/pp.17.01810 (2018).

  • Lüdke, D., C. Roth, D. Hartken and M. Wiermer: MOS6 and TN13 in plant immunity. Plant Signal. Behav.13: e1454816, doi:10.1080/15592324.2018.1454816 (2018).

  • Schmitz, L., S. McCotter, M. Kretschmer, J.W. Kronstad and K. Heimel: Transcripts and tumors: regulatory and metabolic programming during biotrophic phytopathogenesis. F1000Research 7(F1000 Faculty Rev):1812, doi:10.12688/f1000research.16404.1(2018).

  • Sun, T., L. Busta, Q. Zhang, P. Ding, R. Jetter and Y. Zhang:TGACG-BINDING FACTOR 1 (TGA1) and TGA4 Regulate Salicylic Acid and Pipecolic Acid Biosynthesis by Modulating the Expression of SYSTEMIC ACQUIRED RESISTANCE DEFICIENT 1 (SARD1) and CALMODULIN-BINDING PROTEIN 60g (CBP60g). New Phytologist 217(1):344-354, doi:10.1111/nph.14780 (2018).

  • Wu, D., Y. Liu, F. Xu and Y. Zhang: Differential requirement of BAK1 C-terminal tail in development and immunity. J Integr Plant Biol 60:270-275, doi:10.1111/jipb.12623 (2018).


  • Dean, G.H., Z.Q. Jin, L. Shi, E. Esfandiari, R. McGee, K. Nabata, T. Lee, L. Kunst, T.L. Western and G.W. Haughn: Identification of a seed coat-specific promoter fragment from the Arabidopsis MUCILAGE-MODIFIED4 gene. Plant Mol Biol 95:33–50, doi:10.1007/s11103-017-0631-7 (2017).

  • He, Z., T. Huang, K. Ao, X. Yan, and Y. Huang: Sumoylation, phosphorylation, and acetylation fine-tune the turnover of plant immunity components mediated by ubiquitination. Frontiers in Plant Science 8, 1682, doi: 10.3389/fpls.2017.01682 (2017).

  • Johnson K.C., Zhao J., Wu Z., Roth C., Lipka V., Wiermer M., Li X.: The putative kinase substrate MUSE7 negatively impacts the accumulation of NLR proteins. Plant J. 89(6):1174-1183, doi:10,1111/tpj.13454 (2017)

  • Tong, M., T. Kotur, W. Liang, K. Vogelmann, T. Kleine, D. Leiste, C. Brieske, S. Yang, D. Lüdke, M. Wiermer, Y. Zhang, X. Li and S. Hoth: E3 ligase SAUL1 serves as a positive regulator of PAMP-triggered immunity and its homeostasis is monitored by immune receptor SOC3. New Phytol. 215(4):1516-1532, doi:10.1111/nph.14678 (2017).

  • Roth, C. #, D. Lüdke#, M. Klenke, A. Quathamer, O. Valerius, G.H. Braus and M. Wiermer: The truncated NLR protein TIR-NBS13 is a MOS6/IMPORTIN-α3 interaction partner required for plant immunity. Plant J 92, 808-821doi:10,111/tpj.13717 (2017). #These authors contributed equally to this work