former Projects Project area A: Organization and function of peptides and proteins in lipid membranes A01 - The contribution of non-covalent interactions for incorporation, organization, and dynamics of peptide helices in lipid membranes (Steinem/Diederichsen) A02 - Probing membrane-peptide and membrane-protein interactions by pulsed EPR spectroscopy (Bennati) A03 - Lipid-protein interactions underlying mechanosensitivity in K2P K+ channels (de Groot) A04 - Structural and dynamical studies of β-strand-membrane proteins by liquid-/solid-state NMR spectroscopy (Griesinger/Andreas) A05 - Tailor-made glycosphingolipids as a toolkit to investigate domain formation and lipid-protein interactions (Steinem/Werz) A10 - Quantifying diffusion and dynamics of lipids within membranes in a leaflet-dependent manner (Enderlein) A11 - Lipid- and ligand-dependent structure of helical membrane proteins (Zweckstetter) A12 - Mechanisms and dynamics of peptide permeation across membranes probed by molecular simulations (Hub) Project area B: Molecular structures in membrane-membrane interactions B01 - Structural aspects of membrane fusion by X-ray diffraction and imaging (Salditt) B02 - Primary lipid vesicle fusion events: Pathways, forces, energetics (Grubmueller) B03 - The role of proteins on fusion and fission: computer simulation of coarse-grained models (Müller) B04 - Membrane fusion assayed by pore-spanning lipid bilayers Summary (Steinem) B05 - Construction of novel hybrid biooligomers as artificial SNAREs to dissect the mechanism of SNAREs in membrane docking and fusion (Diederichsen/Jahn) B06 - Confocal fluorescence detection of docking and fusion of single proteoliposomes - focus on a novel SNARE hybrid complex (Jahn/Walla) B08 - A quantitative assessment of the role of lateral tension, curvature, and external forces in membrane fusion (Janshoff) B09 - Functional analysis of membrane remodeling by epsin1 (Meinecke) Service projects Ö01 - Making science visible: information, motivation and participation in formal and non-formal educational offers Z02 - Statistical methods for time-varying electrophysiological data and for protein-membrane interactions (Munk) Former Projects A06 - Structural insights into protein-ligand-membrane interactions of the bacterial membrane protein MraY: synthesis and application of chemical probes (Ducho) A07 - Mechanical channel gating and on-chip protein expression for direct insertion of membrane proteins (Schmidt) A09 - Membrane binding mechanism of the peripheral membrane protein pyruvate oxidase from Escherichia coli (Tittmann)
