Publications

2017

• Kuhlmann JW., Junius M., Diederichsen U., Steinem C., Biophys. J. 2017 112(11) 2348-2356, DOI: 10.1016/j.bpj.2017.04.032
  "SNARE-Mediated Single-Vesicle Fusion Events with Supported and Freestanding Lipid Membranes"



• Middel S., Panse CH., Nawratil S., Diederichsen U., Chem. Bio. Chem. 2017 18(23) 2328-32, DOI: 10.1002/cbic.201700487
  "Native Chemical Ligation Directed by Photocleavable Peptide Nucleic Acid (PNA) Templates"



• Moroder L., Kiso Y., Diederichsen U., Teshima T., Beilstein J. Pept. Sci. 2017 23(7-8) 471, DOI: 10.1002/psc.3030
  "Editorial"

2016

• Halbmair K., Wegner J., Diederichsen U., Bennati M., Biophys. J. 2016 111(11) 2345-2348, DOI: 10.1016/j.bpj.2016.10.022
  "Pulse EPR Measurements of Intramolecular Distances in a TOPP-Labeled Transmembrane Peptide in Lipids"



• Kanlidere Z., Jochim O., Cal M., Diederichsen U., Beilstein J. Org. Chem. 2016 12 2136-2144, DOI: 10.3762/bjoc.12.203
  "DNA functionalization by dynamic chemistry"



• Milovanovic D., Platen M., Junius M., Diederichsen U., Schaap IAT., Honigmann A., Jahn R., van den Bogaart G.J. Biomol. Chem. 2016 291 (15) 7868-76, DOI: 10.1074/jbc.M116.716225
  "Calcium Promotes the Formation of Syntaxin 1 Mesoscale Domains through Phosphatidylinositol 4,5-Bisphosphate"



• Moroder L., Diederichsen U., J. Pept. Sci. 2016 22(5) 245, DOI: 10.1002/psc.2892
  "Editorial: A Tribute to Stephen B. H. Kent: Towards a new world of proteins enabled by chemical synthesis"



• Pahlke DM., Diederichsen U., J. Pept. Sci. 2016 22(10) 636-641, DOI: 10.1002/psc.2912
  "Synthesis and characterization of β-peptide helices as transmembrane domains in lipid model membranes"



• Pawar NJ., Diederichsen U., Dhavale DD., Org. Biomol. Chem. 2016 14(2) 785, DOI: 10.1039/c5ob90206a
  "Correction: Multivalent presentation of carbohydrates by 3(14)- helical peptide templates: synthesis, conformational analysis using CD spectroscopy and saccharide recognition"



• Pawar NJ., Diederichsen U., Dhavale DD, Org. Biomol. Chem. 2016 14(2) 785, DOI: 10.1039/c5ob90206a
  "Multivalent presentation of carbohydrates by 3(14)-helical peptide templates: synthesis, conformational analysis using CD spectroscopy and saccharide recognition (vol 13, pg 11278, 2015)"



• Rost U., Steinem C., Diederichsen U., Chem. Sci. 2016 7(9) 5900-5907, DOI: 10.1039/c6sc01147k
  "beta-Glutamine-mediated self-association of transmembrane betapeptides within lipid bilayers"



• Rost U., Xu Y., Salditt T., Diederichsen U., Chem. Phys. Chem. 2016 17(16) 2525-34,
  DOI: 10.1002/cphc.201600289
  "Heavy-Atom Labeled Transmembrane β-Peptides: Synthesis, CD-Spectroscopy, and X-ray Diffraction Studies in Model Lipid Multilayer"



• Sadek M., Berndt D., Milovanovic D., Jahn R., Diederichsen U., Chem. Bio. Chem. 2016 17(6) 479-85, DOI: 10.1002/cbic.201500517
  "Distance Regulated Vesicle Fusion and Docking Mediated by β-Peptide Nucleic Acid SNARE Protein Analogues"



• Wehland JD., Lygina AS., Kumar P., Guha S., Hubrich BE., Jahn R., Diederichsen U., Mol. Biosyst. 2016 12(9) 2770-76, DOI: 10.1039/c6mb00294c
  "Role of the transmembrane domain in SNARE protein mediated membrane fusion: peptide nucleic acid/peptide model systems"

2015

• N. J. Pawar, D. D. Dhavale, U. Diederichsen, Org. Biomol. Chem, 2015, 13, 11278-11285, DOI: 10.1039/C5OB01673H
  
  "Multivalent Presentation of Carbohydrates in 314-Helical Peptide Templets: Synthesis, Conformatinal analysis and Saccharide Recognition"



• H. Rao, M. S. Damian, A. Alshiekh, S. K. C. Elmroth, U. Diederichsen, Org. Biomol. Chem, 2015, 13, 11704-11713, DOI: 10.1039/C5OB01885D
  
  "Design, synthesis and DNA interaction of chimera between a platinum complex and an IHF mimicking peptide"



• S. Kabatas, I.-C. Vreja, S. K. Saka, C. Höschen, K. Kröhnert, F. Opazo, S. O. Rizzoli, U. Diederichsen, Chem. Comm., 2015, 51, 13221-13224, DOI: 10.1039/C5CC03895B
  
  "A contamination-insensitive probe for imaging specific biomolecules by secondary ion mass spectrometry"



• S. Dickgießer, N. Rasche, D. Nasu, S. Middel, S. Hörner, O. Avrutina, U. Diederichsen, H. Kolmar, ACS Chem. Biol., 2015, 10, 2158-2165, DOI: 10.1021/acschembio.5b00315
  
  "Self-assembled hybrid aptamer-Fc conjugates for targeted delivery - a modular chemoenzymatic approach"



• P. Kumar, S. Guha, U. Diederichsen, J. Pept. Sci., 2015, 21, 621-629, DOI: 10.1002/psc.2773
  
  " SNARE Protein Analogue Mediated Membrane Fusion"



• C. Nadler, A. Nadler, C. Hansen, U. Diederichsen, Eur. J. Org. Chem., 2015, 3095-3102, DOI: 10.1002/ejoc.201500033
  
  "A novel photocleavable auxiliary for Extended Native Chemical Ligation"



• I.-C. Vreja, S. Kabatas, S. K. Saka, K. Kröhnert, C. Höschen, F. Opazo, U. Diederichsen, S. O. Rizzoli, Angew. Chem., 2015, 127, 5876-5880, DOI: 10.1002/ange.201411692; Angew. Chem. Int. Ed., 2015, 54, 5784-5788, DOI: 10.1002/anie.201411692
  
  "Secondary ion mass spectrometry of genetically-encoded targets"



• D. Milovanovic, A. Honigmann, S. Koike, F. Göttfert, G. Pähler, M. Junius, S. Müllar, U. Diederichsen, A. Janshoff, H. Grübmuller, H. J. Risselada, C. Eggeling, S. W. Hell, G. van den Bogaart, R. Jahn, Nat. Comm., 2015, 6, 5984, DOI: 10.1038/ncomms6984
  
  "Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains"

2014

• U. Diederichsen, Jahrbuch der Akademie der Wissenschaften zu Göttingen 2013, De Gruyter, Berlin, 2014, 3, 159-167
  "Chemie mit DNA und Peptiden: von präbiotischer Chemie zu Mechanismen in der Biochemie"



• U. M. Kotyrba, K. Pröpper, E.-F. Sachs, A. Myanovska, T. Joppe, F. Lissy, H. Laatsch, G. M. Sheldrick, K. Koszinowski, U. Diederichsen, ChemistryOpen, 2014, 3, 152-160, DOI: 10.1002/open.201400001
  
  Triostin A derived cyclopeptide as architectural template for the alignment of four recognition units,



• N. J. Pawar, N. S. Sidhu, G. M. Sheldrick, D. D. Dhavale, U. Diederichsen, Beilstein J. Org. Chem, 2014, 10, 948-955, DOI: 10.3762/bjoc.10.93
  
  "Molecular architecture with carbohydrate functionalized β-peptides adopting 314-helical conformation"



• D. Matthesa, V. Daebel, K. Meyenberg, D. Riedel, G. Heim, U. Diederichsen, A. Lange, B. L. de Groot, J. Mol. Biol., 2014, 426, 362-376, DOI: 10.1016/j.jmb.2013.10.020
  
  "Spontaneous aggregation of the insulin-derived steric zipper peptide VEALYL results in different aggregation forms with common features"

2013

• S. Guha, J. Graf, B. Göricke, U. Diederichsen, J. Pept. Sci., 2013, 19, 415-422, DOI: 10.1002/psc.2514
  
  "Nucleobase caged peptide nucleic acids: PNA/PNA duplex destabilization and light triggered PNA/PNA recognition"



• T. Hotz , O. Schütte, H. Sieling , T. Polupanow, U. Diederichsen, C. Steinem, A. Munk, NanoBioScience, 2013, 12 , 376-386, DOI: 10.1109/TNB.2013.2284063
  
  "Idealizing ion channel recordings by jump segmentation and statistical multiresolution analysis IEEE Trans on"



• A. Honigmann, G. van den Bogaart, E. Iraheta, H. J. Risselada, D. Milovanovic, V. Müller, S. Müllar, U. Diederichsen, D. Fasshauer, H. Grubmüller, S. W. Hell, C. Eggeling, K. Kühnel, R. Jahn, Nat. Struct. Mol. Biol., 2013, 20, 679–686, DOI: 10.1038/nsmb.2570
  
  "Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment"



• I. Tkach, S. Pornsuwan, C. Höbartner, F. Wachowius, S. Th. Sigurdsson, T. Y. Baranova, U. Diederichsen, G. Sicoli, M. Bennati, Phys. Chem. Chem. Phys., 2013, 15, 3433-3437, DOI: 10.1039/C3CP44415E
  
  "Orientation selection in distance measurements between nitroxide spin labels at 94 GHz EPR with variable dual frequency irradiation"

2012

• G. Portella, T. Polupanow, F. Zocher, D. A. Boytsov, P. Pohl, U. Diederichsen, B. L. de Groot, Biophys J., 2012, 103, 1698-1705, DOI: 10.1016/j.bpj.2012.08.059
  
  "Design of Peptide-Membrane Interactions to Modulate Single-File Water Transport through Modified Gramicidin Channels"



• G. Pähler, C.Panse, U. Diederichsen, A. Janshoff, Biophys J., 2012, 103, 2295–2303, DOI: 10.1016/j.bpj.2012.08.053
  
  "Coiled-Coil Formation on Lipid Bilayers—Implications for Docking and Fusion Efficiency"



• J. A. Cuesta-Seijo, J. Zhang, U. Diederichsen, G. M. Sheldrick, Acta Crystallographica Section D, 2012, D68, 1067-1070, DOI: 10.1107/S090744491202118X
  
  "Continuous ß-turn fold of an alternating alanyl/homoalanyl peptide nucleic acid"



• G. van den Bogaart, K. Meyenberg, U. Diederichsen, R. Jahn, J. Biol. Chem., 2012, 287, 16447-16453, DOI: 10.1074/jbc.M112.343418
  
  "Phosphatidylinositol 4,5-bisphosphate increases the Ca2+ affinity of synaptotagmin-1 40-fold"



• F.Stein, T. Mehmood, T. Plass, J. H. Zaidi, U. Diederichsen, Beilstein J. Org. Chem., 2012, 8, 1576–1583, DOI: 10.3762/bjoc.8.180
  
  "Synthesis of trifunctional cyclo-ß-tripeptide templates"



• S. Scholz, E. K. Liebler, B. Eickmann, H.-J. Fritz, U. Diederichsen, Amino Acids, 2012, 43, 289-298, DOI: 10.1007/s00726-011-1073-1
  
  "Variation of the intercalating proline in artificial peptides mimicking the DNA binding and bending IHF protein"



• B. Holzberger, J. Strohmeier, V. Siegmund, U. Diederichsen, A. Marx, Bioorg. Med. Chem. Lett., 2012, 22, 3136-3139, DOI: 10.1016/j.bmcl.2012.03.056
  
  "Enzymatic synthesis of 8-vinyl- and 8-styryl-2'-deoxyguanosine modified DNA - novel fluorescent molecular probes"



• S. Müllar, J. Strohmeier, U. Diederichsen, Org. Lett., 2012, 14, 1382-1385, DOI: 10.1021/ol3000603
  
  "8-Vinylguanine nucleo amino acid - a fluorescent PNA building block"



• F. Fehr, A. Nadler, F. Brodhun, I. Feussner, U. Diederichsen, ChemistryOpen, 2012, 1, 26-32, DOI: 10.1002/open.201100002
  
  "Semi-Synthesis and Analysis of chemically modified Zif268 Zinc Finger Domains"

2011

• U. Diederichsen, 'Aus den Elfenbeintürmen der Wissenschaft, XLAB Science Festival', E.-M. Neher (Ed.), Band 5, Wallstein Verlag, Göttingen 2011, 111-123.
  "Lineare molekulare Architekturen mit DNA- und Peptid-Biooligomer-Gerüsten"



• G. van den Bogaart, K. Meyenberg, H. J. Risselada, H. Amin, K. I. Willig, B. E. Hubrich, M. Dier, S. W. Hell, H. Grubmüller, U. Diederichsen, R. Jahn, Nature, 2011, 479, 552-555, DOI: 10.1038/nature10545
  
  "Membrane protein sequestering by ionic-protein lipid interactions"



• S. Stoller, G. Sicoli, T. Y. Baranova, M. Bennati, U. Diederichsen, Angew. Chem., 2011, 123, 9917-9920, DOI: 10.1002/ange.201103315
  ; Angew. Chem. Int. Ed., 2011, 50, 9743-9746, DOI: 10.1002/anie.201103315
  
  "TOPP – A Novel Nitroxide-labeled Amino Acid for EPR Distance Measurements"



• A. S. Lygina, K. Meyenberg, R. Jahn, U. Diederichsen, Angew. Chem., 2011, 123, 8756-8760, DOI: 10.1002/ange.201101951
  ; Angew. Chem. Int. Ed., 2011, 50, 8597-8601, DOI: 10.1002/anie.201101951
  
  "Transmembrane Domain Peptide/Peptide Nucleic Acid Hybrid as a Model of a SNARE Protein in Vesicle Fusion"



• K. Meyenberg, A. S. Lygina, G. van den Bogaart, R. Jahn, U. Diederichsen, Chem. Comm., 2011, 47 (33), 9405-9407, DOI: 10.1039/C1CC12879E
  
  "SNARE derived peptide mimic inducing membrane fusion"



• K. E. Otto, S. Hesse, T. N. Wassermann, C. A. Rice, M. A. Suhm, T. Stafforst, U. Diederichsen, PhysChemChemPhys, 2011, 13, 14119-14130, DOI: 10.1039/C1CP20883G
  
  "Temperature-dependent intensity anomalies in amino acid esters: weak hydrogen bonds in protected glycine, alanine and valine"



• J. Strohmeier, I. Hertel, U. Diederichsen, M. G. Rudolph, D. Klostermeier, Biol. Chem., 2011, 392, 357-369, DOI: 10.1515/BC.2011.034
  
  "Changing nucleotide specificity of the DEAD-box helicase Hera abrogates communication between the Q-motif and the P-loop"



• A. Nadler, J. Strohmeier, U. Diederichsen, Angew. Chem., 2011, 123, 5504-5508, DOI: 10.1002/ange.201100078; Angew. Chem. Int. Ed., 2011, 50, 5392-5396, DOI: 10.1002/anie.201100078
  
  "8-Vinyl-2'-deoxyguanosine as Fluorescent 2'-Deoxyguanosine Mimic for Investigating DNA Hybridization and Topology"



• G. v. d. Bogaart, S. Thutupalli, J. H. Risselada, K. Meyenberg, M. Holt, D. Riedel, U. Diederichsen, S. Herminghaus, H. Grubmüller, R. Jahn, Nature Struct. Mol. Biol., 2011, 18, 805-812, DOI: 10.1038/nsmb.2061
  
  "Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation"



• A. Nadler, C. Koch, F. Brodhun, J.-D. Wehland, K. Tittmann, I. Feussner, U. Diederichsen, ChemBioChem, 2011, 12, 728-737, DOI: 10.1002/cbic.201000669
  
  "Influence of substrate dideuteration on the reaction of the bifunctional heme enzyme psi factor producing oxygenase A (PpoA)"



• P. E. Schneggenburger, A. Beerlink, B. Weinhausen, T. Salditt, U. Diederichsen, Eur. Biophys. J., 2011, 40, 417-436, DOI: 10.1007/s00249-010-0645-4
  
  "Peptide Model Helices in Lipid Membranes – Insertion, Positioning and Lipid Response on Aggregation Studied by X-Ray Scattering"



• E.-F. Sachs, A. Nadler, U. Diederichsen, Amino Acids, 2011, 41, 449-456, DOI: 10.1007/s00726-010-0764-3
  
  " Triostin A derived hybrid for simultaneous DNA binding and metal coordination"

2010

• M. S. Damian, H. K. Hedman, S. K. C. Elmroth, U. Diederichsen, Eur. J. Org. Chem., 2010, 6161-6170, DOI: 10.1002/ejoc.201000677
  
  "Synthesis and DNA Interaction of Platinum Complex/Peptide Chimera as Potential Drug Candidates"



• J. Strohmeier, A. Nadler, D. Heinrich, A. Fitzner, U. Diederichsen, Heterocycles, 2010, 82, 713-728, DOI: 10.3987/COM-10-S(E)51
  
  "Synthesis of 8,1'-etheno and 8,2'-ethano bridged guanosine derivatives using radical cyclization"



• P. E. Schneggenburger, S. Müllar, B. Worbs, C. Steinem, U. Diederichsen, J. Am. Chem. Soc., 2010, 132, 8020-8028, DOI: 10.1021/ja1006349
  
  "Molecular Recognition at the Membrane-Water Interface: Controlling Integral Peptide Helices by Off-Membrane Nucleobase Pairing"




• G. N. Roviello, S. Gröschel, C. Pedone, U. Diederichsen, Amino Acids, 2010, 38, 1301-1309, DOI: 10.1007/s00726-009-0324-x
  
  "Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA-chimeras"



• C. P. Sommerhoff, O. Avrutina, H.-U. Schmoldt, D. Gabrijelcic-Geiger, U. Diederichsen and H. Kolmar, J. Mol. Biol., 2010, 395, 167-195, DOI: 10.1016/j.jmb.2009.10.028
  
  "Engineered Cystine Knot Miniproteins as Potent Inhibitors of Human Mast Cell Tryptase β"



• P. E. Schneggenburger, B. Worbs, U. Diederichsen, J. Pept. Sci., 2010, 16, 10-14, DOI: 10.1002/psc.1202
  
  "Azide reduction during peptide cleavage from solid support - the choice of thioscavenger?"

2009

• C. Kleimann, A. Sischka, A. Spiering, K. Tönsing, N. Sewald, U. Diederichsen, D. Anselmetti, Biophys. J., 2009, 97, 2780-2784, DOI: 10.1016/j.bpj.2009.09.001
  
  "Binding kineticx of bisintercalator Triostin A with optical tweezers force mechanistics"



• U. Diederichsen, ChemBioChem, 2009, 10, 2717-2719, DOI: 10.1002/cbic.200900543
  
  "Dynamic Sequence Modification: A Design Principle for Synthetic Informational Oligomers"



• A. Kumar Ray, U. Diederichsen, Eur. J. Org. Chem., 2009, 4801-4809, DOI: 10.1002/ejoc.200900530
  
  "Syntheses of Triostin A Antibiotic and Nucleobase-Functionalized Analogs as New DNA Binders"



• R. Srivastava, A. Kumar Ray, U. Diederichsen, Eur. J. Org. Chem., 2009, 4793-4800, DOI: 10.1002/ejoc.200900511
  
  "Higher Aggregation of ß-Peptide Networks Controlled by Nucleobase Pairing"



• O. Avrutina, M. Empting, S. Fabritz, M. Daneschdar, H. Frauendorf, U. Diederichsen, H. Kolmar, Org. Biomol. Chem., 2009, 7, 4177-4185, DOI: 10.1039/B908261A
  
  "Application of copper(I) catalyzed azide-alkyne [3+2] cycloaddition to the synthesis of template-assembled multivalent peptide conjugate"



• A. Nadler, C. Hain, U. Diederichsen, Eur. J. Org. Chem., 2009, 4593-4599, DOI: 10.1002/ejoc.200900472
  
  "Histidine Analog Amino Acids Providing Metal-Binding Sites Derived from Bioinorganic Model Systems"



• P. E. Schneggenburger, A. Beerlink, B. Worbs, T. Salditt, U. Diederichsen, ChemPhysChem 2009, 10, 1567-1576, DOI: 10.1002/cphc.200900241
  
  "A Novel Heavy Atom Label for Side Specific Peptide Iodination – Synthesis, Membrane Incorporation and X-ray Reflectivity"



• D. Heinrich, U. Diederichsen, M. G. Rudolph, Chem. Eur. J., 2009, 15, 6619-6625, DOI: 10.1002/chem.200900397
  
  "Lys314 is a nucleophile in non-classical reactions of Orotidine-5'-Monophosphate Decarboxylase"



• N. Diezemann, L. M. M. Weigang, P. Chakraborty, H. Frauendorf, T. Letzel, U. Diederichsen, J. Mass. Spectrom. 2009, 44, 794-802, DOI: 10.1002/jms.1557
  
  "Organization of Nucleobase Functionalized ß-Peptides Investigated by Soft Electrospray Ionization Mass Spectrometry"

2008

• J. Wittmann, D. Heinrich, U. Diederichsen, M. G. Rudolph, Biophys. J., 2008, 94, 368-371, DOI: 10.1016/S0006-3495(08)79062-3
  
  "1094-Pos Crystal Structures of Human Orotidine-5'-Monophosphate Decarboxylase - Implications for Drug Design and Catalysis"



• A. Heitz, O. Avrutina, D.-L. Nguyen, U. Diederichsen, J.-F. Hernandez, J. Gracy, H. Kolmar, L. Chiche, BMC Structural Biology, 2008, 8:54, DOI: 10.1186/1472-6807-8-54
  
  "Knottin cyclization: Impact on Structure and Dynamics"



• M. Pitulescu, M. Grapp, R. Krätzner, W. Knepel, U. Diederichsen,Eur. J. Org. Chem., 2008, 2100-2106, DOI: 10.1002/ejoc.200701178
  
  "Synthesis of formacetal linked dinucleotides to facilitat dsDNA bending and binding to the homeodomain of PAx6"



• A. Nadler, U. Diederichsen, Eur. J. Org. Chem., 2008, 1544-1549, DOI: 10.1002/ejoc.200700991
  
  "Guanosine analog with respect to Z-DNA stabilization: Nucleotide with combined C8-bromine and C2'-arabino ethynyl modifications"



• A. Fitzner, H. Frauendorf, H. Laatsch, U. Diederichsen,Anal. Bioanal. Chem., 2008, 390, 1139-1147, DOI: 10.1007/s00216-007-1737-6
  
  "Formation of gutingimycin: analytical investigation of trioxacarcin A mediated alkylation of dsDNA"



• O. Avrutina, H.-U. Schmoldt, D. Gabrijelcic-Geiger, A. Wentzel, H. Frauendorf, C. P. Sommerhoff, U. Diederichsen, H. Kolmar, ChemBioChem, 2008, 9, 33-37, DOI: 10.1002/cbic.200700452
  
  "Head-to-tail cyclized cystine-knot peptides by a combined recombinant and chemical route of synthesis"



• J. Wittmann, D. Heinrich, K. Gasow, A. Frey, U. Diederichsen, M. G. Rudolph, Structure, 2008, 16, 82-92, DOI: 10.1016/j.str.2007.10.020
  
  "Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design"

2007

• D. Heinrich, T. Wagner, U. Diederichsen, Org. Lett., 2007, 9, 5311-5314, DOI: 10.1021/ol7025334
  
  "Synthesis and DNA incorporation of an Ethynyl-Bridged Cytosine C-Nucleoside as Guanosine"



• L. F. Tietze, T. Eicher, U. Diederichsen, A. Speicher,Wiley-VCH, Weinheim, September 2007.
  "Reactions and Syntheses in the Organic Chemistry Laboratory"



• A. Küsel, Z. Khattari, P. E. Schneggenburger, A. Banerjee, T. Salditt, U. Diederichsen, ChemPhysChem, 2007, 8, 2336-2343, DOI: 10.1002/cphc.200700477
  
  "Conformation and interaction of a D,L-alternating peptide with bilayer membrane: X-ray reflectivity, CD and FTIR spectroscopy"



• A. Weiß , U. Diederichsen, Eur. J. Org. Chem., 2007, 5531-5539, DOI: 10.1002/ejoc.200700444
  
  "Uniformly nucleobase functionalized ß-peptide helices: Watson-Crick pairing of non-specific aggregation"



• N. Hildebrandt, D. Hermsdorf, R. Signorell, S. A. Schmitz, U. Diederichsen, ARKIVOC, 2007, 5, 79-90, online
  
  "Superparamagnetic iron oxide nanoparticles functionalized with peptides by electrostatic interactions"



• T. Stafforst, U. Diederichsen, Eur. J. Org. Chem., 2007, 899-911, DOI: 10.1002/ejoc.200600729
  
  "Synthesis of Alaninyl and N-(2-Aminoethyl)glycinyl Amino Acid Derivatives Containing the Green Fluorescent Protein Chromophore in Their Side Chains for Incorporation into Peptides and Peptide Nucleic Acids"



• T. Stafforst, U. Diederichsen, Eur. J. Org. Chem., 2007, 681-688, DOI: 10.1002/ejoc.200600747
  
  "Solid-phase synthesis of acid-sensitive N-(2-aminoethyl)glycine-PNA oligomers via Fmoc/Bhoc-strategy"

2006

• T. Stafforst, U. Diederichsen, Angew. Chem., 2006, 118, 5502-5506, DOI: 10.1002/ange.200600150; Angew. Chem. Int. Ed., 2006, 45, 5376-5380, DOI: 10.1002/anie.200600150
  
  "Thymine Oxetanes as Charge Traps for Chemical Monitoring of Nucleic Acid Mediated Transfer of Excess Electrons"



• P. Chakraborty, A. M. Brückner, U. Diederichsen, Eur. J. Org. Chem., 2006, 2410-2416, DOI: 10.1002/ejoc.200501003
  
  "Synthesis of a 7-Deazaguanine-Functionalized ß-Amino Acid: Improved Specificity of ß-Peptide Helix Organization"

2005

• O. Avrutina, H.-U. Schmoldt, D. Gabrijelcic-Geiger, D. Le Nguyen, C. P. Sommerhoff, U. Diederichsen, H. Kolmar, Biol. Chem., 2005, 386, 1301-1306, DOI: 10.1515/BC.2005.148
  
  "Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II"



• A. Küsel, J. Zhang, M. Alvarino Gil, C. A. Stückl, W. Meyer-Klaucke, F. Meyer, U. Diederichsen, Eur. J. Inorg. Chem., 2005, 4317-4324, DOI: 10.1002/ejic.200500464
  
  "Metal binding within a peptide-based nucleobase stack with tuneable double strand topology"



• T. Stafforst, U. Diederichsen, Chem. Comm., 2005, 3430-3432, DOI: 10.1039/B503699B
  
  "(6-4)-Photolyase activity requires a charge shift reaction"



• P. Chakraborty, U. Diederichsen, Chem. Eur. J. 2005, 11, 3207-3216, DOI: 10.1002/chem.200500004
  
  "Three Dimensional Organization of Helices: Design Principles for Nucleobase-Functionalized ß-Peptides"



• B. Abel, A. Charvat, U. Diederichsen, M. Faubel, B. Girmann, J. Niemeyer, A. Zeeck,Int. J. Mass Spectr. 2005, 243, 177-188, DOI: 10.1016/j.ijms.2005.02.008
  
  "Applications, features, and mechanistic aspects of liquid water beam desorption mass spectrometry"



• U. Diederichsen, D. Weicherding, N. Diezemann, Org. Biomol. Chem. 2005, 3, 1058-1066, DOI: 10.1039/B411545G
  
  "Side chain homologation of alanyl peptide nucleic acids: pairing selectivity and stacking"



• B. Dietrich, U. Diederichsen,Eur. J. Org. Chem. 2005, 147-153, DOI: 10.1002/ejoc.200400548
  
  "Synthesis of Cyclopeptidic Analogues of Triostin A with Quinoxalines or Nucleobases as Chromophores"

2004

• O. Avrutina, H.-U. Schmoldt, H. Kolmar, U. Diederichsen, Eur. J. Org. Chem. 2004, 4931-4935, DOI: 10.1002/ejoc.200400440
  
  "Fmoc-Assisted Synthesis of a 29-Residue Cystine-Knot Trypsin Inhibitor Containing a Guaninyl Amino Acid at the P1-Position"



• E. Alexopoulos, A. Küsel, G. M. Sheldrick, U. Diederichsen, I. Usón, Acta Cryst. 2004, D60, 1971-1980, DOI: 10.1107/S0907444904022292
  
  "Solution and structure of an alternating D,L-peptide"



• E. K. Liebler, U. Diederichsen, Org. Lett. 2004, 6, 2893-2896, DOI: 10.1021/ol049016a
  
  "From IHF Protein to Design and Synthesis of a Sequence-Specific DNA Bending Peptide"



• K. B. Lorenz, U. Diederichsen, J. Org. Chem. 2004, 69, 3917-3927, DOI: 10.1021/jo0496805
  
  "Solution-Phase Synthesis of Nucleobase-Substituted Analogues of Triostin A"



• D. Weicherding, W. B. Davis, S. Hess, T. von Feilitzsch, M. E. Michel-Beyerle, U. Diederichsen, Bioorg. Med. Chem. Lett. 2004, 14, 1629-1632, DOI: 10.1016/j.bmcl.2004.01.068
  
  "Femtosecond Time-Resolved Guanine Oxidation in Acridine Modified Alanyl Peptide Nucleic Acids"

2003

• B. Lorenz, U. Diederichsen, Letters in Peptide Science 2003, 10, 111-117, DOI: 10.1023/B:LIPS.0000032374.98648.7b
  
  "Nucleo Amino Acids as Arginine Mimetics in Cyclic Peptides"



• A. M. Brückner, P. Chakraborty, S. H. Gellman, U. Diederichsen, Angew. Chem. 2003, 115, 4532-4536, DOI: 10.1002/ange.200351871; Angew. Chem. Int. Ed. 2003, 42, 4395-4399, DOI: 10.1002/anie.200351871
  
  "Molecular Architecture with Functionalized ß-Peptide Helices"



• A. M. Brückner, M. Garcia, A. Marsh, S. H. Gellman, U. Diederichsen, Eur. J. Org. Chem. 2003, 3555-3561, DOI: 10.1002/ejoc.200300269
  
  "Synthesis of Novel Nucleo-ß-Amino Acids and Nucleobase-Functionalized ß-Peptides"



• T. Wagner, W. B. Davis, K. B. Lorenz, M. E. Michel-Beyerle, U. Diederichsen, Eur. J. Org. Chem. 2003, 3673-3679, DOI: 10.1002/ejoc.200300242
  
  "Synthesis of Amino Acids with Unnatural Nucleobases or Chromophores Suitable for Use in Model Electron-Transfer Studies"



• U. Diederichsen, Fluorous Techniques: Progress in Reaction-Processing and Purification, in "Organic Synthesis- Highlights V" Hrsg. H.-G. Schmalz, T. Wirth, Wiley-VCH, Weinheim 2003, 93-104.



• U. Diederichsen, Bryostatin and their Analogues, in "Organic Synthesis- Highlights V" Hrsg. H.-G. Schmalz, T. Wirth, Wiley-VCH, Weinheim 2003, 307-316.



• U. Diederichsen, Eleutherobin: Synthesis, Structure/Activity Relationship, and Pharmacophore, in "Organic Synthesis- Highlights V" Hrsg. H.-G. Schmalz, T.Wirth, Wiley-VCH, Weinheim 2003, 317-325.



• U. Diederichsen, K. B. Lorenz, Total Synthesis of the Natural Products CP-263, 114 and CP-225, 917, in "Organic Synthesis- Highlights V" Hrsg. H.-G. Schmalz, T. Wirth, Wiley-VCH, Weinheim 2003, 326-341.



• U. Diederichsen, T. Wagner, Solid-Phase Synthesis of Oligosaccharides, in "Organic Synthesis- Highlights V" Hrsg. H.-G. Schmalz, T. Wirth, Wiley-VCH, Weinheim 2003, 384-394.

2002

• Arndt M. Brückner, Harald W. Schmitt, Ulf Diederichsen, Helv. Chim. Acta 2002, 85, 3855-3866, DOI: 10.1002/1522-2675(200211)85:11<3855::AID-HLCA3855>3.0.CO;2-A
  
  "Nucleo-ß-Amino Acids: Synthesis and Oligomerization to ß-Homoalanyl-PNA"

2000

• M. F. H. Hoffmann, A. M. Brückner, T. Hupp, B. Engels, U. Diederichsen, Helv. Chim. Acta 2000, 83, 2580-2593, DOI: 10.1002/1522-2675(20000906)83:9<2580::AID-HLCA2580>3.0.CO;2-6
  
  "Specific Purine-Purine Base Pairing in Linear Alanyl Peptide Nucleic Acids"



• U. Diederichsen, C. Biro, Bioorg. Med. Chem. Lett. 2000, 10, 1417-1420, DOI: 10.1016/S0960-894X(00)00231-6
  
  "Phe and Asn Side Chains in DNA Double Strands"

1999

• U. Diederichsen, D. Weicherding,Synlett 1999, S1, 917-920, DOI: 10.1055/s-1999-3117
  
  "Interactions of Amino Acid Side Chains with Nucleobases in Alanyl-PNA"



• U. Diederichsen, Nachr. Chem. Tech. Lab. 1999, 47, 432-438, DOI: 10.1002/nadc.19990470424
  
  "Kostensenker. Bryostatine und ihre Analoga"



• U. Diederichsen, Nachr. Chem. Tech. Lab. 1999, 47, 673-676, DOI: 10.1002/nadc.19990470619
  
  "Oligosaccharid Festphasensynthese"



• U. Diederichsen, Nachr. Chem. Tech. Lab. 1999, 47, 805-809, DOI: 10.1002/nadc.19990470722
  
  "Chemie mit Fluorphasen: Vorteile für Reaktionsführung und Aufarbeitung"



• U. Diederichsen, Nachr. Chem. Tech. Lab. 1999, 47, 1228-1233, DOI: 10.1002/nadc.19990471014
  
  "Synthese, Struktur-Aktivitäts-Beziehung Pharmakophor von Eleutherobin"



• U. Diederichsen,Nachr. Chem. Tech. Lab. 1999, 47, 1423-1427, DOI: 10.1002/nadc.19990471214
  
  "Totalsynthese der Naturstoffe CP-263,114 und CP 225,917"



• U. Diederichsen, T. Lindhorst, L. A. Wessjohann, B. Westermann, "Bioorganic Chemistry - Highlights and New Aspects",Hrsg. Wiley-VCH, Weinheim 1999.



• U. Diederichsen, T. Lindhorst, L. A. Wessjohann, B. Westermann, Alanyl-PNA: A Model System for DNA Using a Linear Peptide Backbone as Scaffold, U. Diederichsen, in "Bioorganic Chemistry - Highlights and New Aspects" Hrsg. Wiley-VCH, Weinheim 1999, 255-261.



• U. Diederichsen, Trendbericht Organische Chemie 1998, Teil I; Nachr. Chem. Tech. Lab. 1999, 47, 171-175, DOI: 10.1016/10.1002/nadc.19990470210
  
  "Nucleinsäure-Analoga und neuartige Peptidstrukturen"

1998

• U. Diederichsen, Angew. Chem. 1998, 110, 2395-2397, DOI: 10.1002/(SICI)1521-3757(19980817)110:16<2395::AID-ANGE2395>3.0.CO;2-9
  ; Angew. Chem. Int. Ed. 1998, 37, 2273-2276, DOI: 10.1002/(SICI)1521-3773(19980904)37:16<2273::AID-ANIE2273>3.0.CO;2-P
  
  "Oligomers with Intercalating Cytosine-Cytosine+ Base Pairs and Peptide Backbone: DNA i-Motif Analogues"



• U. Diederichsen, Angew. Chem. 1998, 110, 1745-1747, DOI: 10.1002/(SICI)1521-3757(19980619)110:12<1745::AID-ANGE1745>3.0.CO;2-1
  ; Angew. Chem. Int. Ed. 1998, 37, 1655-1657, DOI: 10.1002/(SICI)1521-3773(19980703)37:12<1655::AID-ANIE1655>3.0.CO;2-2
  
  "Selectivity of DNA Replication: The Importance of Base-Pairs Geometry over Hydrogen Bonding"



• U. Diederichsen, H. W. Schmitt, Eur. J. Org. Chem. 1998, 827-835, DOI: 10.1002/(SICI)1099-0690(199805)1998:5<827::AID-EJOC827>3.0.CO;2-B
  
  "ß-Homoalanyl-PNA: A Special Case of ß-Peptides with ß-Sheet-Like Backbone Conformation, Organization in Higher Ordered Structures"



• U. Diederichsen,Bioorg. Med. Chem. Lett. 1998, 8, 165-168, DOI: 10.1016/S0960-894X(97)10210-4
  
  "Alanyl-PNA Homoduplex: A-T Pairing with the N7-Regioisomer of Adenine"



• U. Diederichsen, H. W. Schmitt, Angew. Chem. 1998, 110, 312-315, DOI: 10.1002/(SICI)1521-3757(19980202)110:3<312::AID-ANGE312>3.0.CO;2-E
  ; Angew. Chem. Int. Ed. 1998, 37, 302-305, DOI: 10.1002/(SICI)1521-3773(19980216)37:3<302::AID-ANIE302>3.0.CO;2-4
  
  "ß-Homoalanyl-PNA: Synthesis and Indication of Higher Ordered Structures"



• K. Groebke, J. Hunziker, W. Fraser, L. Peng, U. Diederichsen, K. Zimmermann, A. Holzner, C. Leumann, A. Eschenmoser, Helv. Chim. Acta 1998, 81, 375 - 474, DOI: 10.1002/hlca.19980810302
  
  "Warum Pentose- und nicht Hexose-Nucleinsäuren? Teil V: (Purin-Purin-Basenpaarung in der Homo-DNS-Reihe: Guanin, Isoguanin, 2,6-Diaminopurin und Xanthin)"

1997

• U. Diederichsen, Angew. Chem. 1997, 109, 1966-1969, DOI: 10.1002/ange.19971091726
  ;Angew. Chem. Int. Ed. Engl. 1997, 36, 1886-1889, DOI: 10.1002/anie.199718861
  
  "Alanyl-PNA: Evidence for Linear Band Structures Based on Guanine-Cytosine Base Pairs"



• U. Diederichsen, Bioorg. Med. Chem. Lett. 1997, 7, 1743-1746, DOI: 10.1016/S0960-894X(97)00302-8
  
  "Alanyl-PNA Oligomers: A New System for Intercalation"



• D. P. Curran, U. Diederichsen, M. Palowich, J. Am. Chem. Soc. 1997, 119, 4797-4804, DOI: 10.1021/ja970219m
  
  "Radical Cyclizations of Acylgermanes. New Reagent Equivalents of the Carbonyl Radical Acceptor Synthon"



• U. Diederichsen, D. P. Curran, J. Organomet. Chem. 1997, 531, 9-12, DOI: 10.1016/S0022-328X(96)06677-6
  
  "Biomolecular Reactions of Alkyl Halides and Acylgermanes: Formation of Ketones, Diketons, and other Products by Radical-Radical Reaction"

1996

• U. Diederichsen, H. W. Schmitt, Tetrahedron Lett. 1996, 37, 475-478, DOI: 10.1016/0040-4039(95)02216-3
  
  "Self-Pairing PNA with Alternating Alanyl-/Homoalanyl Backbone"



• U. Diederichsen, Angew. Chem. 1996, 108, 458-461, DOI: 10.1002/ange.19961080412
  ; Angew. Chem. Int. Ed. Engl. 1996, 35, 445-448, DOI: 10.1002/anie.199604451
  
  "Pairing Properties of Alanyl Peptide Nucleic Acids Containing an Amino Acid Backbone with Alternating Configuration"

1993

• U. Diederichsen, Dissertation ETH Nr. 10122, Zürich 1993.
  "A. Hypoxanthin-Basenpaarungen in HOMO-DNA-Oligonucleotiden; B. Zur Frage des Paarungsverhaltens von Glucopyranosyl-Oligonucleotiden"



• J. Hunziker, H.-J. Roth, M. Böhringer, A. Giger, U. Diederichsen, M. Göbel, R. Krishnan, B. Jaun, C. Leumann, A. Eschenmoser Helv. Chim. Acta 1993, 76, 259-352, DOI: 10.1002/hlca.19930760119
  
  "Warum Pentose- und nicht Hexose-Nucleinsäuren? Teil III: Oligo(2’,3’-dideoxy-b-D-glucopyranosyl)nucleotide ('HOMO-DNS'): Paarungseigenschaften"